Carbon Monoxide Poisoning:
- Carbon monoxide (CO) is removed via the pulmonary circulation through competitive binding of hemoglobin by oxygen.
- The half-life of carboxyhemoglobin (COHb) in a patient breathing room air is approximately 300 minutes; this decreases to 90 minutes with ***high-flow oxygen via a nonrebreathing mask.***
- The most important interventions in the management of a CO-poisoned patient are prompt removal from the source of CO and institution of high-flow oxygen by nonrebreathing face mask.